The Role of TGF β 1 and IL-13 in Cellular Signal Transduction of Hepatic Fibrosis of Schistosomiasis TGF-β1与IL-13在血吸虫病肝纤维化细胞信号转导中的作用
Influence of spleen preservation on hepatic fibrosis and relevant cytokine in rabbits with advanced schistosomiasis 保脾手术对晚期血吸虫病肝纤维化及相关细胞因子的影响
Relationship between hepatic fibrosis degree of schistosomiasis Japonic and the levels of hyaluronic acid, tumour necrosis factor 血吸虫病肝纤维化程度与血清透明质酸和肿瘤坏死因子水平的关系
Evaluation of the Animal Model of Hepatic Fibrosis Caused by Schistosomiasis 血吸虫病肝纤维化实验动物模型的建立与评价
Ultrastructural studies on effects of colchicine in treating hepatic fibrosis of schistosomiasis rabbits 秋水仙碱治疗家兔血吸虫病肝纤维化超微结构研究
Methods CT features in 23 cases of hepatic cirrhosis caused by schistosomiasis were analysed retrospectively, including the shape, size, edges, density, calcification and complication. 方法回顾分析23例血吸虫性肝硬化的CT征象,包括肝脏形态、大小、轮廓、密度、钙化及合并症等。
Inhibitory effect of prostaglandin E_1 on activation of hepatic stellate cells in rabbits with schistosomiasis 前列腺素E1抑制血吸虫病家兔肝脏星状细胞活化研究
Objective To analyse the CT manifestations of hepatic cirrhosis caused by schistosomiasis. 目的分析血吸虫性肝硬化的CT表现。
Methods Using immunohistochemical technique to observe the changes of the distribution and content of hepatic type ⅰ、ⅲ、ⅵ collagen proteins in schistosomiasis mice with liver fibrosis before and after colchicine treatment. 方法应用免疫组化技术,观察血吸虫病肝纤维化小鼠在秋水仙碱治疗前后肝脏Ⅰ、Ⅲ、Ⅵ型胶原蛋白的分布及含量(半定量)变化。
Histological data showed that 22 cases ( 47.8%) were diagnosed as hepatic fibrosis induced by schistosomiasis, 16 ( 34.8%) as hepatic fibrosis complicated by chronic active hepatitis ( CAH), and 8 ( 17.4%) as nodular cirrhosis. 组织学资料显示,22例患者(47.8%)为血吸虫性肝纤维化,合并慢活肝者达16例(34.8%),8例(17.4%)为结节性肝硬变。
Conclusion Colchicine treatment could reduce the content of hepatic type ⅲ and ⅵ collagen proteins significantly in schistosomiasis mice with liver fibrosis, thereby, play its role against hepatic fibrosis. 结论秋水仙碱治疗可显著降低血吸虫感染小鼠肝内Ⅲ型和Ⅵ型胶原蛋白含量,从而发挥其抗肝纤维化作用。
Conclusion It is important to go on with further study on the effect of cellular factors on hepatic fibrosis of schistosomiasis japonica. 结论:深入研究细胞因子在肝纤维化形成机制中的作用有重要意义。
Study on the expression of hepatic procollagen mRNA in Schistosomiasis with liver fibrosis 血吸虫病肝纤维化过程中肝脏前胶原mRNA的表达变化研究
Conclusion The therapeutic effect of vitamin E in the treatment of hepatic fibrosis of schistosomiasis is satisfactory, safe and easy. 结论维生素E治疗血吸虫病肝纤维化疗效显著。
Comparative study on hepatic and intestinal pathological changes in different animals with schistosomiasis japonica 不同动物宿主血吸虫病肝肠病理变化的比较观察
The Changes of Hepatic Function in Schistosomiasis Patients before and after Antimony Treatment and its Clinical Significance 血吸虫病锑剂治疗前后某些肝功能的变化及其临床意义
Conclusion PGE 1 significantly suppressed hepatic fibrogenesis in schistosomiasis japonica, whose mechanism was probably associated with suppressing of TGF-β 1 expression by PGE 1. 结论PGE1对日本血吸虫病肝纤维化的形成有抑制作用,其机理可能与PGE1抑制TGF-β1的表达有关。
The expression of IFN-γ and hepatic fibrosis in the liver of dying patients of schistosomiasis 晚期血吸虫病患者肝脏中γ干扰素的表达与肝纤维化
Egg granuloma formation and subsequently hepatic fibrosis are the main pathological basis of schistosomiasis Japonica. 血吸虫虫卵引起的肉芽肿以及随之发生的纤维化是血吸虫病的主要病理基础。
Effect on changes of ultrastructure and pathology of hepatic tissue in domestic rabbit suffering from Japonica schistosomiasis hepatic fibrosis treated with ribonucleic acid 核糖核酸对家兔日本血吸虫性肝纤维化病理及超微结构变化的影响
This paper reports on the hepatic pathological changes in 106 clinically diagnosed advanced schistosomiasis japonica cases from 1977-1981 in our hospital. 本文报道我院1977~1981年106例临床诊断为晚期血吸虫病手术时所取肝组织活检结果。
The Matched Control Analysis of Misdiagnosis Hepatic Schistosomiasis to Hepatocarcinoma by CT and Pathology 肝血吸虫病误诊肝癌CT与病理对照分析
The effect of pHGF on TNF in liver and hepatic fibrosis in schistosomiasis japonica pHGF对日本血吸虫病宿主肝内TNF及肝纤维化的影响
Objective To explore the effects of colchicine on the expression of hepatic collagen proteins in schistosomiasis mice with liver fibrosis. 目的阐明秋水仙碱治疗对血吸虫病肝纤维化小鼠肝脏胶原蛋白表达的影响。
Objective To explore the classification of ultrasound images of hepatic parenchyma of schistosomiasis japonica. 目的提出日本血吸虫病肝脏超声显像肝实质图像的分类。
Effects of pentoxifylline on expressions of hepatic Bcl-2 and Bax protein in schistosomiasis mice with liver fibrosis 己酮可可碱对血吸虫病肝纤维化小鼠肝组织Bcl-2,Bax表达的影响
Evaluation and control of diseases were related to the progress and prognosis of chronic hepatic diseases, especially for viral hepatitis, alcoholic hepatic disease, hepatic disease in schistosomiasis, fatty liver and etc, an irreversible progress to the hepatic cirrhosis would happen without treating promptly. 尤其是病毒性肝炎、酒精性肝病、血吸虫性肝病、脂肪肝等慢性肝病,慢性肝纤维化的过程若未得到及时控制,将进一步进展为难以逆转的肝硬化失代偿期。
Experimental model of hepatic fibrosis due to schistosomiasis was estabilished: Balb/ c mice were infected by Schistosoma japonicum cercariae through their abdominal skins, comparing with mice in normal group untreated. 建立实验性血吸虫病肝纤维化小鼠模型:采用Balb/c小鼠,用血吸虫尾蚴经腹部皮肤感染,同时设正常对照组比较。
Our results might provide the experimental basis for PAE as a natural therapeutic agent to prevent hepatic fibrosis of schistosomiasis japonica. 以上研究结果将为PAE开发成治疗血吸虫病肝纤维化中药新药提供了实验依据。
This work may give us a new idea on prevention and treatment for hepatic fibrosis with schistosomiasis japonicum. 本研究对血吸虫病HF的预防和治疗提供了新的思路。